Coming from a cultured background, she took classes in Mons with M. Putsage (pastel), Anto-Carte and E. Motte, but she was mainly self-taught. She exhibited regularly from 1922, notably invited by the Groupe Nervia and Le Bon Vouloir (Mons). She was awarded the Charles Caty prize in 1963.

Andrée Bosquet mainly painted and drew (oils, red chalk and charcoal), with simplicity and elegance, self-portraits and portraits of children, delicate but without mawkishness, restful and clear still lifes and exquisitely fragile bouquets. His choice is for soft, fine, half-toned colours and round, sculptural forms. Her style does not belong to any school defined by the history of art, even if it has been compared to that of the Florentine primitives or found to share common features with naive art or symbolism. In all her work, she has followed a line, an inner thread, a search for the essential and for purity from which she has never allowed herself to be distracted.